Breakthrough Breast Cancer scientists, using data from the Breakthrough Generations Study, have pinpointed a change in DNA which links hormone levels with the risk of breast cancer in younger women for the first time. The gene is linked to a slightly reduced risk of breast cancer in premenopausal women.
The gene identified is important because it is involved in breaking down drugs used to treat breast cancer. It could lead to doctors being able to know which treatment, and what dose, a patient needs so more women can survive the disease. These important results would not have been possible without the Breakthrough Generations Study, which has over 115,000 female participants with the aim of finding the causes of breast cancer.
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